Users' Guide:Prognosis
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Are the results valid?
What are the results?
Will the results help me in patient care?

Are the results valid?

Was there a representative and well-defined sample of patients at a similar point in the course of disease?
Was follow-up sufficiently long and complete?
Were objective and unbiased outcome criteria used?
Was there adjustment for important prognostic factors?

What are the results?

How likely are the outcomes over time?
How precise are the estimates of likelihood?

Will the results help me in patient care?

Were the study patients similar to my own?
Will the results lead directly to selecting therapy?
Are the results useful for reassuring patients?

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